Anatomy and Physiology Lecture Notes
Unit 6 - The
Muscular System
A. Muscular System Introduction
- Muscles convert chemical energy into mechanical energy.
- Muscles make up the bulk of the body and account for about one-third of its
weight.
- Their ability to contract not only enables the body to move, but also provides the
force that pushes substances, such as blood and food, through the body.
- Without the muscular system, none of the other organ systems would be able to
function.
B. Types of Muscle Tissue
1. Skeletal Muscle Cells are striated (striped) with multiple nuclei; are arranged as
many, long, cylindrical cells bundled together; with several bundles enclosed in
tough connective tissue sheath to form a muscle; they are responsible for
voluntary movement, and are generally connected to bones via tendons

2. Smooth Muscle Cells are not striated, have a single nucleus; the cells are
tapered at both ends, are held together by tight junctions; and are located in the
walls of "hollow organs" i.e., blood vessels, stomach, bladder, and other internal
organs; they are responsible for involuntary movements i.e., peristalsis, and
although they are wrapped by connective tissue, they are not connected by
tendons. Although considered involuntary muscles, they do respond to
psychological states such as stress and excitement

3. Cardiac Muscle Cells are striated with multiple nuclei per cell like skeletal
muscles; however, the cells are branched and connected end-to-end by junctions
(fused cell membranes) that allow electrical current flow; they are located only in
the heart wall. Although also considered involuntary muscles, they do respond to
psychological states such as stress and excitement, and significant evidence
suggests that some degree of voluntary control can be gained over cardiac
muscles, through practices such as meditation and biofeedback

C. Functional Organization of Skeletal Muscle
1) Single Muscle
Fibers
1. A muscle fiber is a single, multinucleated muscle cell.
2. A muscle is made up of hundreds or even thousands of muscle fibers,
depending on the muscles size.
3. Although muscle fiber makes up most of the muscle tissue, a large amount of
connective tissue, blood vessels, and nerves are also present.
4. Connective tissue covers and supports each muscle fiber and reinforces the
muscle as a whole.
5. The health of muscle depends on a sufficient nerve and blood supply. Each
skeletal muscle has a nerve ending that controls its activity (innervation), and an
individual system to supply and drain blood (vascularization).
2) Bundles of Muscles
6. Muscle Fibers consist of bundles of threadlike structures called myofibrils.
7. Each myofibril is made up of two types of protein filaments- Thick ones and
Thin ones.
8. The thick filaments are made up of a protein called myosin.
9. The thin filaments are made of a protein called actin.
10. Myosin and Actin filaments are arranged to form overlapping patterns, which
are responsible for the light and dark bands (striations) that can be seen in skeletal
muscle.
11. Thin actin filaments are anchored at their midpoints to a structure called the
z-line.
12. The region from one z-line to the next is called a sarcomere, which is the
functional unit of muscle contractions.

D.
How Muscles and Bones Interact
1. Skeleton muscles generate force and produce movement only by contracting or
pulling on body parts.
2. Individual muscles can only pull; they cannot push.
3. Skeleton muscles are joined to bone by tough connective tissue called tendons.
4. Tendons attach muscle to bone; the origin is the more stationary bone, the
insertion is the more movable bone.
5. Tendons are attached in such a way that they pull on the bones and make them
work like levers. The movements of the muscles and joints enable the bones to act
as levers.
6. Most skeletal muscles work in pairs.
7. When one muscle or set of muscles contracts, the other relaxes.
8. The muscles of the upper arm are a good example of this dual action: a flexor,
is a muscle that bends a joint, while an extensor is a muscle that straightens a
joint.
a. when the biceps muscle (on the front of the upper arm, flexor)
contracts, it bends or flexes the elbow joint.
b. when the triceps muscle (on the back of the upper arm, extensor)
contracts, it opens, or extends, the elbow joint.
c. a controlled movement requires contraction by both muscles.

E. Names of Skeletal Muscles
Individual muscles are named on the basis of several
criteria, each of which focuses on a particular structural or functional
characteristic. Paying close attention to these cues can greatly simplify your
task of learning muscle names and actions:
The rectus
femoris is a straight muscle of the thigh. The external
oblique is a muscle slanted across the abdomen.
The gluteus maximus
is the largest muscle of the gluteus muscle group.
The temporalis
and frontalis muscles overlie the temporal and
frontal bones of the skull.
The biceps, triceps,
and quadriceps have two, three, and four origins respectively.
The sternocleidomastoid
muscle has its origin on the sternum (sterno)
and clavicle (cleido) and inserts on the mastoid
process of the temporal bone.
The deltoid muscle is
roughly triangular. (Deltoid means "triangular".)
